TOKYO, June 29 (Xinhua) -- Tokyo stocks opened mixed Friday on buying spurred by Wall Street's advance overnight and selling based on investor consternation over ongoing U.S.-China trade tensions.

As of 9:15 a.m. local time, the 225-issue Nikkei Stock Average edged up 16.44 points, or 0.07 percent, from Thursday to 22,286.83.

The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, lost 2.70 points, or 0.16 percent, to 1,724.30.

Pharmaceutical and air transportation issues comprised notable advancers, while mining, oil and coal product, insurance and miscellaneous financial issues led those that declined the most in the opening minutes after the morning bell.